BofA下調Denali Therapeutics股票目標價，因ALS試驗未達關鍵終點

2025-01-09 12:39:57 | als

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• 2024-11-28 04:49 PTC Therapeutics ALS drug fails to meet endpoints as trials shut down - Clinical Trials Arena
• 2024-11-27 09:45 PTC axes utreloxastat program after phase 2 ALS failure - Fierce Biotech
• 2024-11-26 22:17 PTC Therapeutics discontinues development of ALS drug after trial failure - Reuters.com
• 2024-11-27 09:05 Blood-brain barrier breakthrough for ALS and Alzheimer’s disease - Drug Target Review
• 2024-11-26 06:30 MaaT Pharma Announces Positive Phase 1b Results, Meeting Primary Endpoint in the Evaluation of MaaT033 in Amyotrophic Lateral Sclerosis (ALS) - Business Wire
• 2024-11-26 12:28 Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB - Molecular Neurodegeneration
• 2024-11-26 13:18 Lilly to develop ALS therapies against targets ID’d with Verge tech - ALS News Today
• 2024-08-13 07:00 Preventing ALS: Is it possible? - Medical News Today
• 2024-11-22 18:22 ALS Research Accelerated with New iPSC Repository - RegMedNet
• 2024-11-22 16:33 FDA Grants Orphan Drug Designation to RAG-21 for Treatment of ALS - Pharmacy Times
• 2024-11-05 08:00 Network medicine informed multiomics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis - Nature.com
• 2024-11-27 18:52 Martha Silano’s forthcoming book, “Terminal Surreal,” explores her terminal illness diagnosis - University of Washington Magazine
• 2024-05-13 07:00 A promising new study could lead to a reduction in symptoms of amyotrophic lateral sclerosis (ALS) - The Conversation
• 2024-11-27 12:50 PTC Scraps ALS Asset Utreloxastat After Mid-Stage Fail, Analysts Look to PKU Opportunity - BioSpace
• 2024-11-29 03:15 How one New Orleans family’s views on Thanksgiving and gratitude changed after a devastating diagnosis - FOX 8 Local First
• 2024-11-26 12:00 MaaT Pharma eyes Phase II after early success in ALS microbiome trial - Clinical Trials Arena
• 2024-11-28 15:40 Why I can be thankful in the bad situation of life with ALS - ALS News Today
• 2024-07-19 07:00 Voice signals database of ALS patients with different dysarthria severity and healthy controls - Nature.com
• 2024-07-08 07:00 Temporal stratification of amyotrophic lateral sclerosis patients using disease progression patterns - Nature.com
• 2024-11-25 13:09 FDA grants orphan drug status to RAG-21 for treating FUS-ALS - ALS News Today
• 2024-11-25 04:40 Doctor's 18-yr term for consensual killing of ALS sufferer upheld - Kyodo News Plus
• 2024-10-31 07:00 Mitochondrial genetics shed light on ALS Risk and protection - News-Medical.Net
• 2024-06-19 07:00 Mechanism of motoneuronal and pyramidal cell death in amyotrophic lateral sclerosis and its potential therapeutic modulation - Nature.com
• 2024-06-25 11:50 Oligodendrocytes in amyotrophic lateral sclerosis and frontotemporal dementia: the new players on stage - Frontiers
• 2024-11-27 10:19 PTC halts development of ALS drug after trial miss - The Pharma Letter
• 2024-11-27 16:18 AI-Powered Communication Solution for People Living With ALS Revealed at Lenovo Tech World - AccessWire
• 2024-11-28 03:17 Anime Last Stand (ALS) Codes (November 2024) - Beebom
• 2024-06-21 07:00 Scientists identify genes linked to brain cell loss in ALS - National Institutes of Health
• 2024-11-22 20:13 A Mom Is Always a Mom: An ALS Caregiver Story - ALS Association
• 2024-06-26 09:50 Depletion of perivascular macrophages delays ALS disease progression by ameliorating blood-spinal cord barrier impairment in SOD1G93A mice - Frontiers
• 2024-11-14 08:00 John Driskell Hopkins on ALS research and coping with his diagnosis: "I am going to sing through it" - CBS News
• 2024-11-08 08:00 Key Pathway Leading to Neurodegeneration in Early Stages of ALS Identified - University of California San Diego
• 2024-11-26 21:17 2024 Joel C. Mayo ALS 25-A Graduation - aetc.af.mil
• 2024-10-03 07:00 Creation of de novo cryptic splicing for ALS and FTD precision medicine - Science
• 2024-11-12 08:00 Fueled by a ‘fall off your chair’ discovery and $101 million, Trace launches to take on ALS - STAT
• 2024-06-27 12:25 The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches - Frontiers
• 2024-05-20 07:00 The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology - Nature.com
• 2024-11-27 19:00 IIT-BHU developing med device with potential to cure sclerosis - The Times of India
• 2024-08-03 07:00 Heterozygous knockout of Synaptotagmin13 phenocopies ALS features and TP53 activation in human motor neurons - Nature.com
• 2024-06-26 20:36 Motoneuron firing in amyotrophic lateral sclerosis (ALS) - Frontiers
• 2024-11-25 09:54 Osaka court upholds 18-year sentence for murder of ALS patient - The Japan Times
• 2024-11-26 22:06 PTC Therapeutics to End Development of ALS Treatment - MarketWatch
• 2024-11-20 10:00 Verge Genomics Announces Milestones in Collaboration with Lilly to Discover and Develop Novel Treatments for ALS - GlobeNewswire
• 2024-11-25 12:18 Steve Gleason, former NFL player battling ALS, suffers accident following volleyball clinic - Fox News
• 2024-09-10 07:00 New target identified for potential ALS therapy - News-Medical.Net
• 2024-11-27 15:28 Breakthrough could provide early detection of ALS, FTD - WAFB
• 2024-05-18 07:00 Efficacy of non-pharmacological interventions for individuals with amyotrophic lateral sclerosis: systematic review and network meta-analysis of randomized control trials - Nature.com
• 2024-09-17 07:00 Resistance exercise in early-stage ALS patients, ALSFRS-R, Sickness Impact Profile ALS-19, and muscle transcriptome: a pilot study - Nature.com
• 2024-11-26 08:16 IIT-BHU developing cell-based medical device for potential cure of Amyotrophic Lateral Sclerosis - The Times of India
• 2024-11-26 22:50 ALS NETWORK RECOGNIZES NATIONAL FAMILY CAREGIVERS MONTH - PR Newswire
• 2024-03-11 07:00 PCDHA9 as a candidate gene for amyotrophic lateral sclerosis - Nature.com
• 2024-06-26 22:31 A Gut Feeling in Amyotrophic Lateral Sclerosis: Microbiome of Mice and Men - Frontiers
• 2024-09-12 07:00 Breakthrough technique may help speed understanding, treatment of MD, ALS - Harvard Gazette
• 2024-11-28 00:40 Macquarie University Spinout Secures Landmark $16.75M Funding for Breakthrough ALS Gene Therapy - News Hub
• 2024-11-06 08:00 National Institute on Aging invests an additional $7.3 million into NU-9 - Northwestern Now
• 2024-07-30 19:38 Transcranial static magnetic stimulation for amyotrophic lateral sclerosis: a bicentric, randomised, double-blind placebo-controlled phase 2 trial - The Lancet
• 2024-03-11 07:00 Evidence for disrupted copper availability in human spinal cord supports Cu - Nature.com
• 2024-11-12 08:00 National ALS Registry Newsletter and ALS Act - CDC
• 2024-07-04 07:00 Brain–body mechanisms contribute to sexual dimorphism in amyotrophic lateral sclerosis - Nature.com
• 2024-06-07 07:00 Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target - Nature.com
• 2024-05-20 07:00 Multidisciplinary care for amyotrophic lateral sclerosis - The Lancet
• 2024-10-25 07:00 Accelerating Access to Critical Therapies for ALS Act – ACT for ALS - FDA.gov
• 2024-03-26 07:00 Neuromuscular organoids model spinal neuromuscular pathologies in C9orf72 amyotrophic lateral sclerosis - ScienceDirect.com
• 2024-11-28 00:02 Macquarie University spinout secures landmark funding for breakthrough ALS gene therapy - Biotech Dispatch
• 2024-05-16 07:00 TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression - Nature.com
• 2024-08-14 07:00 New brain-computer interface allows man with ALS to ‘speak’ again - UC Davis Health
• 2024-10-17 07:00 ALS took a young mother's voice away. AI helped her regain it - ABC News
• 2024-06-12 07:00 M6A reduction relieves FUS-associated ALS granules - Nature.com
• 2024-11-27 18:51 Breakthrough could provide early detection of ALS, FTD - WAFB
• 2024-10-22 07:00 This 35-year-old woman has ALS – and wants to make you laugh - USA TODAY
• 2024-06-12 07:00 Q&A: New Frontiers in ALS Research - Cedars-Sinai
• 2024-11-28 17:31 Charles Barkley jokes about violent urges against ex-Auburn teammate over rivalry - Marca English
• 2024-07-23 07:00 Targeting C9orf72 in people with ALS - The Lancet
• 2024-10-08 07:00 Research Spotlight: The Role of Diabetes and Diet in Preventing ALS - ALS Association
• 2024-11-27 10:38 Kronos, Idorsia plan layoffs; PTC shelves ALS drug - Yahoo Finance
• 2024-06-22 07:00 An EEG & eye-tracking dataset of ALS patients & healthy people during eye-tracking-based spelling system usage - Nature.com
• 2024-08-15 07:00 Text-to-speech brain implant restores ALS patient's voice - Reuters
• 2024-05-13 21:47 AMP Amyotrophic Lateral Sclerosis - The Foundation for the National Institutes of Health
• 2024-09-24 07:00 Mayo Clinic awarded federal grant to study experimental ALS drug - Mayo Clinic
• 2024-08-29 07:00 ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes - Nature.com
• 2024-05-22 05:49 Advancements and challenges in amyotrophic lateral sclerosis - Frontiers
• 2024-05-02 07:00 Epigenomic analysis sheds light on risk factors for ALS - MIT News
• 2024-07-09 07:00 ALS Nexus: Mapping Out the Future of ALS - ALS Association
• 2024-11-01 19:21 Cliff and Brooke Eby: A Caregiver Story - ALS Association
• 2024-11-26 21:30 PTC Therapeutics' ALS Drug Trial Fails Key Endpoints, Development Halted | PTCT Stock News - StockTitan
• 2024-08-15 07:00 Is ALS contagious? Understanding the causes of ALS - Medical News Today
• 2024-07-03 07:00 Let's See Quicker Diagnoses - ALS Association
• 2024-08-23 07:00 Brooke Eby: An ALS Hero - ALS Association
• 2024-05-21 07:00 Swedish neurologists warn ALS patients may have to self-pay for new gene therapy - EURACTIV
• 2024-08-16 07:00 Katie Adams: An ALS Hero - ALS Association
• 2024-09-18 07:00 Researchers use artificial intelligence to help ALS patient speak again - CBS Boston
• 2024-08-14 07:00 Longevity of a Brain–Computer Interface for Amyotrophic Lateral Sclerosis - nejm.org
• 2024-11-28 02:19 ALS gene therapy biotech startup Celosia Therapeutics raises $16.75m - Business News Australia
• 2024-10-11 07:00 Toxic protein may contribute to ALS development - Penn State University
• 2024-06-07 07:00 Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms - Nature.com
• 2024-11-22 03:07 How AI’s being used to help those with ALS, dementia - The Times of India
• 2024-11-28 15:44 Support Pembrokeshire dad fight against ALS - Herald Wales

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